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VPS37C Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM08484G 100 μl / $495

VPS37C Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM08484G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VPS37C antibody (Center).

Molecular Weight

H=39 KDa

Cellular Localization

Antigen Cellular Localization: Late endosome membrane; Peripheral membrane protein. Note=Probably associates with membranes. Recruited to the plasma membrane by HIV-1

Host

Rabbit

Species Reactivity

Human, Rat

Immunogen

142-169 aa

Target

This VPS37C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the Central region of human VPS37C.

Symbol

PML39

GeneID

UniProt ID

Function

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.

Summary

VPS37C is a subunit of ESCRT-I (endosomal sorting complexrequired for transport I), a complex in the class E vacuolarprotein sorting (VPS) pathway required for sorting ubiquitinatedtransmembrane proteins into internal vesicles of multivesicularbodies (Eastman et al., 2005 [PubMed 15509564]).

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~1:1000

Synonyms

Vacuolar protein sorting-associated protein 37C, hVps37C, ESCRT-I complex subunit VPS37C, VPS37C, PML39

Images

All lanes : Anti-VPS37C Antibody (Center) at 1:1000 dilution Lane 1: Raji whole cell lysate Lane 2: Hela whole cell lysate Lane 3: HT-29 whole cell lysate Lane 4: PC-12 whole cell lysate Lane 5: PC-3 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 39 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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