> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TBP /Transcription factor IID (isoform1) Antibody (N-Term)Brand |
Leading Biology | Catalog Number |
APR13715G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TBP /Transcription factor IID (isoform1) antibody (N-Term).
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Molecular Weight |
37698 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus.
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Host |
Goat
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Species Reactivity |
Human
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Isotype |
IgG
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Symbol |
GTF2D1, TF2D, TFIID
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GeneID |
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UniProt ID |
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Function |
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre- initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
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Summary |
This antibody is expected to recognize reported isoform 1(NP_003185.1) only.
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Form |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Synonyms |
TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit, TBP, GTF2D1, TF2D, TFIID
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Images |
APR13715G (0.3 μg/ml) staining of HeLa nuclear (A) and cytosolic (B) lysates (35 μg protein in commercial extraction buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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