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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > DUOX1 (aa972-985) Antibody (internal region)

DUOX1 (aa972-985) Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APR07629G 0.1 mg / $495

DUOX1 (aa972-985) Antibody (internal region)

Brand

Leading Biology

Catalog Number

APR07629G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DUOX1 (aa972-985) antibody (internal region).

Molecular Weight

177235 Da

Cellular Localization

Antigen Cellular Localization: Apical cell membrane; Multi- pass membrane protein. Note=Localizes to the apical membrane of epithelial cells

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

DUOX, LNOX1, THOX1

GeneID

UniProt ID

Function

Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.

Summary

Reported variants represent identical protein: NP_787954.1, NP_059130.2. This antibody is not expected to cross-react with DUOX2.

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Dual oxidase 1, 1.11.1.-, 1.6.3.1, Large NOX 1, Long NOX 1, NADPH thyroid oxidase 1, Thyroid oxidase 1, DUOX1, DUOX, LNOX1, THOX1

Images

APR07629G (0.1 μg/ml) staining of Human Testis lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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