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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SLC46A1 / PCFT (aa233-247) Antibody (internal region)

SLC46A1 / PCFT (aa233-247) Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APR10109G 0.1 mg / $495

SLC46A1 / PCFT (aa233-247) Antibody (internal region)

Brand

Leading Biology

Catalog Number

APR10109G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLC46A1 / PCFT (aa233-247) antibody (internal region).

Molecular Weight

49771 Da

Cellular Localization

Antigen Cellular Localization: Apical cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Localizes to the apical membrane of intestinal cells in iron-deficient cells, while it resides in the cytoplasm in iron-replete cells.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

HCP1, PCFT

GeneID

UniProt ID

Function

Has been shown to act both as an intestinal proton- coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. Shows a higher affinity for folate than heme.

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Proton-coupled folate transporter, G21, Heme carrier protein 1, PCFT/HCP1, Solute carrier family 46 member 1, SLC46A1, HCP1, PCFT

Images

APR10109G (0.3 μg/ml) staining of Human Liver lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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