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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CYP24A1 Antibody (internal region)

CYP24A1 Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APG02873G 0.1 mg / $495

CYP24A1 Antibody (internal region)

Brand

Leading Biology

Catalog Number

APG02873G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP24A1 antibody (internal region).

Molecular Weight

58875 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion.

Host

Goat

Species Reactivity

Human, Rat

Isotype

IgG

Symbol

CYP24

GeneID

UniProt ID

Function

Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.

Summary

This antibody is expected to recognize both reported isoforms (NP_000773.2; NP_001122387.1).

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

1, 25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, 1.14.13.126, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24A1, CYP24

Images

APG02873G (0.1 μg/ml) staining of Human Liver lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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