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GRM2 Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APR12293G 0.1 mg / $495

GRM2 Antibody (internal region)

Brand

Leading Biology

Catalog Number

APR12293G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRM2 antibody (internal region).

Molecular Weight

95568 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

GPRC1B, MGLUR2

GeneID

UniProt ID

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Summary

This antibody is expected to recognize both isoforms (NP_000830.2; NP_001123535.1).

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Synonyms

Metabotropic glutamate receptor 2, mGluR2, GRM2, GPRC1B, MGLUR2

Images

APR12293G (1 μg/ml) staining of Human Hippocampus lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

APR12293G (3.8 μg/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specification

Quantity

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