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DLL4 Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APR11756G 0.1 mg / $495

DLL4 Antibody (internal region)

Brand

Leading Biology

Catalog Number

APR11756G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DLL4 antibody (internal region).

Molecular Weight

74605 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Goat

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

GeneID

UniProt ID

Function

Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.

Summary

Notch signaling

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4

Images

APR11756G (0.3 μg/ml) staining of Human (A), Mouse(B) and Rat (C) Lung lysates (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

Specification

Quantity

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