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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GCC185 Antibody (internal region)

GCC185 Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APR16093G 0.1 mg / $495

GCC185 Antibody (internal region)

Brand

Leading Biology

Catalog Number

APR16093G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GCC185 antibody (internal region).

Molecular Weight

195910 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

KIAA0336, RANBP2L4

GeneID

UniProt ID

Function

Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2.

Summary

This antibody is expected to recognise both reported isoforms (NP_055450.1and NP_852118.1).

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, E

Synonyms

GRIP and coiled-coil domain-containing protein 2, 185 kDa Golgi coiled-coil protein, GCC185, CLL-associated antigen KW-11, CTCL tumor antigen se1-1, Ran-binding protein 2-like 4, RanBP2L4, Renal carcinoma antigen NY-REN-53, GCC2, KIAA0336, RANBP2L4

Images

APR16093G (3.8 μg/ml) staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specification

Quantity

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