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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CTDSP1 Antibody (internal region)

CTDSP1 Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APR15595G 0.1 mg / $495

CTDSP1 Antibody (internal region)

Brand

Leading Biology

Catalog Number

APR15595G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTDSP1 antibody (internal region).

Molecular Weight

29203 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Note=Colocalizes with RNA polymerase II

Host

Goat

Species Reactivity

Human, Mouse

Isotype

IgG

Symbol

NIF3, NLIIF, SCP1

GeneID

UniProt ID

Function

Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Summary

This antibody is expected to recognise both reported isoforms (NP_067021 and NP_872580)

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Synonyms

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, 3.1.3.16, Nuclear LIM interactor-interacting factor 3, NLI-IF, NLI-interacting factor 3, Small C-terminal domain phosphatase 1, SCP1, Small CTD phosphatase 1, CTDSP1, NIF3, NLIIF, SCP1

Images

APR15595G (0.1 μg/ml) staining of Mouse Testis lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

APR15595G (5 μg/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specification

Quantity

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