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Goat Anti-DTX3 Antibody

Catalog # Availability Size / Price Inquiry
APR16268G 0.1 mg / $495

Goat Anti-DTX3 Antibody

Brand

Leading Biology

Catalog Number

APR16268G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-DTX3 antibody.

Molecular Weight

37988 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Goat

Species Reactivity

Mouse

Isotype

IgG

Symbol

RNF154

GeneID

UniProt ID

Function

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Summary

DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Probable E3 ubiquitin-protein ligase DTX3, 6.3.2.-, Protein deltex-3, Deltex3, RING finger protein 154, DTX3, RNF154

Images

APR16268G (0.3 μg/ml) staining of NIH3T3 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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