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Goat Anti-SUMF1 Antibody

Catalog # Availability Size / Price Inquiry
APR16405G 0.1 mg / $495

Goat Anti-SUMF1 Antibody

Brand

Leading Biology

Catalog Number

APR16405G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-SUMF1 antibody.

Molecular Weight

40556 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum lumen

Host

Goat

Species Reactivity

Human, Mouse

Isotype

IgG

Symbol

FGE

GeneID

UniProt ID

Function

Using molecular oxygen and an unidentified reducing agent, oxidizes a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also called C(alpha)-formylglycine. Known substrates include GALNS, ARSA, STS and ARSE.

Summary

This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Sulfatase-modifying factor 1, 1.8.99.-, C-alpha-formylglycine-generating enzyme 1, SUMF1, FGE

Images

APR16405G (1 μg/ml) staining of Mouse Pancreas lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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