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Goat Anti-STK39 / SPAK Antibody

Catalog # Availability Size / Price Inquiry
AMM05137G 0.1 mg / $495

Goat Anti-STK39 / SPAK Antibody

Brand

Leading Biology

Catalog Number

AMM05137G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-STK39 / SPAK antibody.

Molecular Weight

59474 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Nucleus when caspase-cleaved.

Host

Goat

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Symbol

SPAK

GeneID

UniProt ID

Function

May act as a mediator of stress-activated signals.

Summary

This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Synonyms

STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, 2.7.11.1, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK

Images

AMM05137G (0.5 μg/ml) staining of Jurkat lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

AMM05137G (3.8 μg/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specification

Quantity

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