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Goat Anti-SOD1 Antibody

Catalog # Availability Size / Price Inquiry
AMM05132G 0.1 mg / $495

Goat Anti-SOD1 Antibody

Brand

Leading Biology

Catalog Number

AMM05132G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-SOD1 antibody.

Molecular Weight

15936 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria

Host

Goat

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

GeneID

UniProt ID

Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

Summary

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E, EIA

Synonyms

Superoxide dismutase [Cu-Zn], 1.15.1.1, Superoxide dismutase 1, hSod1, SOD1

Images

AMM05132G (0.02 μg/ml) staining of Mouse Brain lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

AMM05132G (0.01 μg/ml) staining of NIH3T3 (A), HEK293 (B), HepG2 (C) and MCF7 (D) lysates (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

AMM05132G (1.5ug/ml) as the reporter with EB002010 as the capture rabbit antibody (5ug/ml).

Specification

Quantity

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