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Goat Anti-SBP2 Antibody

Catalog # Availability Size / Price Inquiry
AMM05109G 0.1 mg / $495

Goat Anti-SBP2 Antibody

Brand

Leading Biology

Catalog Number

AMM05109G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-SBP2 antibody.

Molecular Weight

95462 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Nucleus.

Host

Goat

Species Reactivity

Human, Mouse

Isotype

IgG

Symbol

SBP2

GeneID

UniProt ID

Function

Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.

Summary

The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, IF, IP, ICC, E

Synonyms

Selenocysteine insertion sequence-binding protein 2, SECIS-binding protein 2, SECISBP2, SBP2

Images

AMM05109G staining of HFF cell lysate with B) 100nM siRNA or A) control siRNA. Detected by chemiluminescence. Data kindly provided by Laura Papp and Kum Kum Khanna, Brisbane, Australia.

AMM05109G (3 μg/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

Specification

Quantity

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