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Goat Anti-PDE4D Antibody

Catalog # Availability Size / Price Inquiry
APR16354G 0.1 mg / $495

Goat Anti-PDE4D Antibody

Brand

Leading Biology

Catalog Number

APR16354G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-PDE4D antibody.

Molecular Weight

91115 Da

Cellular Localization

Antigen Cellular Localization: Apical cell membrane. Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome (By similarity). Colocalized with SHANK2 to the apical membrane of colonic crypt cells.

Host

Goat

Species Reactivity

Human, Mouse

Isotype

IgG

Symbol

DPDE3

GeneID

UniProt ID

Function

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Summary

This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E, EIA

Synonyms

cAMP-specific 3', 5'-cyclic phosphodiesterase 4D, 3.1.4.53, DPDE3, PDE43, PDE4D, DPDE3

Images

APR16354G staining (1 μg/ml) of COS cell lysates (25 μg protein): transfected with Human PDE4D1 (1), transfected with Human PDE4D3 (2), untransfected (3). Primary incubation was 1 hour. Detected by chemiluminescence.

HEK293 overexpressing Human PDE4D2 (RC212410) and probed with APR16354G (mock transfection in first lane), tested by Origene.

Specification

Quantity

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