> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-PDE4D AntibodyBrand |
Leading Biology | Catalog Number |
APR16354G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-PDE4D antibody.
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Molecular Weight |
91115 Da
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Cellular Localization |
Antigen Cellular Localization:
Apical cell membrane. Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome (By similarity). Colocalized with SHANK2 to the apical membrane of colonic crypt cells.
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Host |
Goat
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Species Reactivity |
Human, Mouse
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Isotype |
IgG
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Symbol |
DPDE3
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GeneID |
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UniProt ID |
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Function |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
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Summary |
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
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Form |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E, EIA
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Synonyms |
cAMP-specific 3', 5'-cyclic phosphodiesterase 4D, 3.1.4.53, DPDE3, PDE43, PDE4D, DPDE3
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Images |
APR16354G staining (1 μg/ml) of COS cell lysates (25 μg protein): transfected with Human PDE4D1 (1), transfected with Human PDE4D3 (2), untransfected (3). Primary incubation was 1 hour. Detected by chemiluminescence.
HEK293 overexpressing Human PDE4D2 (RC212410) and probed with APR16354G (mock transfection in first lane), tested by Origene. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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