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Goat Anti-MTHFD1 Antibody

Catalog # Availability Size / Price Inquiry
AMM05040G 0.1 mg / $495

Goat Anti-MTHFD1 Antibody

Brand

Leading Biology

Catalog Number

AMM05040G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-MTHFD1 antibody.

Molecular Weight

101559 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

MTHFC, MTHFD

GeneID

UniProt ID

Summary

This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

C-1-tetrahydrofolate synthase, cytoplasmic, C1-THF synthase, Methylenetetrahydrofolate dehydrogenase, 1.5.1.5, Methenyltetrahydrofolate cyclohydrolase, 3.5.4.9, Formyltetrahydrofolate synthetase, 6.3.4.3, C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed, MTHFD1, MTHFC, MTHFD

Images

AMM05040G (1 μg/ml) staining of Human Substantia Nigra lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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