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Goat Anti-IRF6 Antibody

Catalog # Availability Size / Price Inquiry
APR16310G 0.1 mg / $495

Goat Anti-IRF6 Antibody

Brand

Leading Biology

Catalog Number

APR16310G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-IRF6 antibody.

Molecular Weight

53130 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm Note=Translocates to nucleus in response to an activating signal

Host

Goat

Species Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Function

Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity).

Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Synonyms

Interferon regulatory factor 6, IRF-6, IRF6

Images

APR16310G (2.5 μg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

APR16310G staining (0.2 μg/ml) of Human Ovary lysate (RIPA buffer, 35 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

HEK293 overexpressing IRF6 (RC201579) and probed with APR16310G (mock transfection in first lane), tested by Origene.

Specification

Quantity

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