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Goat Anti-CSNK1E Antibody

Catalog # Availability Size / Price Inquiry
APR16256G 0.1 mg / $495

Goat Anti-CSNK1E Antibody

Brand

Leading Biology

Catalog Number

APR16256G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-CSNK1E antibody.

Molecular Weight

47315 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus

Host

Goat

Species Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Function

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine- induced granuloytic differentiation.

Summary

The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Casein kinase I isoform epsilon, CKI-epsilon, CKIe, 2.7.11.1, CSNK1E

Images

HEK293 overexpressing CSNK1E (RC202436) and probed with APR16256G (mock transfection in first lane), tested by Origene.

Specification

Quantity

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