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Goat Anti-CDX2 Antibody

Catalog # Availability Size / Price Inquiry
APR16249G 0.1 mg / $495

Goat Anti-CDX2 Antibody

Brand

Leading Biology

Catalog Number

APR16249G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-CDX2 antibody.

Molecular Weight

33520 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

CDX3

GeneID

UniProt ID

Function

Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.

Summary

The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2, CDX2, CDX3

Images

APR16249G (1 μg/ml) staining of Human Kidney lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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