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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-14-3-3 sigma / Stratifin Antibody

Goat Anti-14-3-3 sigma / Stratifin Antibody

Catalog # Availability Size / Price Inquiry
APR12060G 0.1 mg / $495

Goat Anti-14-3-3 sigma / Stratifin Antibody

Brand

Leading Biology

Catalog Number

APR12060G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-14-3-3 sigma / Stratifin antibody.

Molecular Weight

27774 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Secreted. Note=May be secreted by a non-classical secretory pathway

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

HME1

GeneID

UniProt ID

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Synonyms

14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin, SFN, HME1

Images

APR12060G (0.1 μg/ml) staining of human skin lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

APR12060G (2μg/ml) staining of paraffin embedded Human Skin. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.

Specification

Quantity

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