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Catalase Antibody (Center)

Catalog # Availability Size / Price Inquiry
APG02435G 100 μl / $495

Catalase Antibody (Center)

Brand

Leading Biology

Catalog Number

APG02435G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Catalase antibody (Center).

Molecular Weight

59756 Da

Cellular Localization

Antigen Cellular Localization: Peroxisome.

Host

Rabbit

Species Reactivity

Human

Target

Catalase

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.

Summary

Catalase is a peroxisome specific marker protein belonging to the catalase family. Defects in the gene encoding for the catalase protein can cause acatalasia, a disease characterized by the absence of catalase activity in red cells and associated with ulcerating oral lesions. Catalase is also an important regulator of oxidative stress and inflammation, and may contribute to the development of rheumatoid arthritis. Catalase, which can form a homotetramer, is found in all nearly all aerobically respiring organisms and functions in protecting cells from the toxic effects of hydrogen peroxide.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, FC

Synonyms

CAT; Catalase

Images

Western blot analysis with Mouse kidney tissue lysates (35 μg/lane). Catalase (arrow) was detected using the purified pAb.

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with Catalase antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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