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CRSP1 Antibody

Catalog # Availability Size / Price Inquiry
APG02789G 100 μl / $495

CRSP1 Antibody

Brand

Leading Biology

Catalog Number

APG02789G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRSP1 antibody.

Molecular Weight

168478 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Note=A subset of the protein may enter the nucleolus subsequent to phosphorylation by MAPK1 or MAPK3

Host

Rabbit

Species Reactivity

Human, Mouse

Target

CRSP1

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Summary

CSP1/TRAP220 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IP

Synonyms

CRSP1, CRSP-1, Cofactor Required for Sp1 Transcriptional Activation 1, TRAP220, Thyroid Hormone Receptor-Associated Protein Complex Component, 220 kD, PPARBP, PPAR Binding Protein, DRIP205, Vitamin D Receptor Interacting Protein Complex Component, 205 kD, DRIP230, Vitamin D Receptor-Interacting Protein, 230 kD, TRIP2, Thyroid Receptor Interacting Protein 2, MED1, PBP, PPARGBP, RB18A

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