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KLF4 Antibody

Catalog # Availability Size / Price Inquiry
APR17030G 100 μl / $495

KLF4 Antibody

Brand

Leading Biology

Catalog Number

APR17030G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KLF4 antibody.

Molecular Weight

54kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Mouse

Species Reactivity

Human

Clone

1E6

Isotype

IgG1

Symbol

EZF, GKLF

GeneID

UniProt ID

Function

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, ICC, E

Dilution

WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 IF~~1/200 - 1/1000

Synonyms

Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4, EZF, GKLF

Images

Figure 1: Western blot analysis using KLF4 mAb against HEK293 (1) and KLF4(AA: 2-180)-hIgGFc transfected HEK293 (2) cell lysate.

Figure 2: Immunohistochemical analysis of paraffin-embedded colon cancer tissues (left) and lung cancer tissues (right) using KLF4 mouse mAb with DAB staining

Figure 3: Immunofluorescence analysis of ECA109 cells using KLF4 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Specification

Quantity

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