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ZYX Antibody (monoclonal) (M02)Brand |
Leading Biology | Catalog Number |
APR14059G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ZYX antibody (monoclonal) (M02).
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Molecular Weight |
61277 Da
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Host |
mouse
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Species Reactivity |
Human, Mouse
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Target |
ZYX (AAH08743, 1 a.a. ~ 572 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone |
2D1
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Isotype |
IgG2a Kappa
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GeneID |
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UniProt ID |
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Summary |
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
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Form |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, E
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Dilution |
WB~~1:500~1000
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Synonyms |
Zyxin, Zyxin-2, ZYX
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Images |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (88.66 KDa) . ZYX monoclonal antibody (M02), clone 2D1 Western Blot analysis of ZYX expression in NIH/3T3 ( (Cat APR14059G ) Immunoperoxidase of monoclonal antibody to ZYX on formalin-fixed paraffin-embedded human spleen. [antibody concentration 1.5 ug/ml] |
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Specification |
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Quantity |
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