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MYO3A Antibody (monoclonal) (M01)Brand |
Leading Biology | Catalog Number |
AMM06526G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MYO3A antibody (monoclonal) (M01).
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Molecular Weight |
186208 Da
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Host |
mouse
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Species Reactivity |
Human
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Target |
MYO3A (NP_059129, 1400 a.a. ~ 1490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone |
8D12
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Isotype |
IgG2b Kappa
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GeneID |
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UniProt ID |
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Summary |
The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea.
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Form |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:500~1000
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Synonyms |
Myosin-IIIa, MYO3A
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Images |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.64 KDa) . MYO3A monoclonal antibody (M01), clone 8D12 Western Blot analysis of MYO3A expression in Hela S3 NE ( (Cat AMM06526G ) Detection limit for recombinant GST tagged MYO3A is approximately 1ng/ml as a capture antibody. |
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Specification |
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Quantity |
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