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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > FKBP5 Antibody (monoclonal) (M02)

FKBP5 Antibody (monoclonal) (M02)

Catalog # Availability Size / Price Inquiry
APR15991G 100 μg / $495

FKBP5 Antibody (monoclonal) (M02)

Brand

Leading Biology

Catalog Number

APR15991G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FKBP5 antibody (monoclonal) (M02).

Molecular Weight

51212 Da

Host

mouse

Species Reactivity

Human

Target

FKBP5 (AAH42605, 1 a.a. ~ 457 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

3D1-1B10

Isotype

IgG2b Kappa

GeneID

UniProt ID

Summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Form

Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Dilution

WB~~1:500~1000

Synonyms

Peptidyl-prolyl cis-trans isomerase FKBP5, PPIase FKBP5, 51 kDa FK506-binding protein, 51 kDa FKBP, FKBP-51, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506-binding protein 5, FKBP-5, FKBP54, p54, HSP90-binding immunophilin, Rotamase, FKBP5, AIG6, FKBP51

Images

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (76.01 KDa) .

Immunofluorescence of monoclonal antibody to FKBP5 on HeLa cell . [antibody concentration 10 ug/ml]

Detection limit for recombinant GST tagged FKBP5 is approximately 0.03ng/ml as a capture antibody.

Specification

Quantity

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