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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > CD282 (Toll-Like Receptor 2) Antibody - Without BSA and Azide

CD282 (Toll-Like Receptor 2) Antibody - Without BSA and Azide

Catalog # Availability Size / Price Inquiry
APR10970G 100 μg / $495

CD282 (Toll-Like Receptor 2) Antibody - Without BSA and Azide

Brand

Leading Biology

Catalog Number

APR10970G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD282 (Toll-Like Receptor 2) antibody - Without BSA and Azide.

Molecular Weight

90kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Mouse

Species Reactivity

Human, Monkey, Drosophila

Clone

TLR2/221

Isotype

Mouse / IgG2a, kappa

Symbol

TIL4

GeneID

UniProt ID

Function

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Summary

This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.?

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, IF, FC

Synonyms

Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4

Images

Specification

Quantity

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