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TSG101 antibody - middle region

Catalog # Availability Size / Price Inquiry
AMM05445G 100 μg / $495

TSG101 antibody - middle region

Brand

Leading Biology

Catalog Number

AMM05445G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TSG101 antibody - middle region.

Molecular Weight

43kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Late endosome membrane; Peripheral membrane protein. Note=Mainly cytoplasmic. Membrane- associated when active and soluble when inactive. Depending on the stage of the cell cycle, detected in the nucleus. Colocalized with CEP55 in the midbody during cytokinesis (By similarity)

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Rabbit, Goat, Horse, Yeast, Bovine, Guinea Pig, Dog

GeneID

UniProt ID

Function

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator (By similarity).

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, Tsg101

Images

WB Suggested Anti-TSG101 Antibody Titration: 2.5μg/ml ELISA Titer: 1:62500 Positive Control: NIH/3T3 cell lysate

Specification

Quantity

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