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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TLE3 antibody - N-terminal region

TLE3 antibody - N-terminal region

Catalog # Availability Size / Price Inquiry
AMM08216G 100 μg / $495

TLE3 antibody - N-terminal region

Brand

Leading Biology

Catalog Number

AMM08216G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TLE3 antibody - N-terminal region.

Molecular Weight

83 kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine

Target

The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.

Symbol

KIAA1547

GeneID

UniProt ID

Function

Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).

Summary

This is a rabbit polyclonal antibody against TLE3. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

Transducin-like enhancer protein 3, Enhancer of split groucho-like protein 3, ESG3, TLE3, KIAA1547

Images

TLE3 antibody - N-terminal region (AMM08216G) in Human HepG2 cells using Western Blot WB Suggested Anti-TLE3 Antibody Titration: 2.5μg/ml Positive Control: HepG2 cell lysate

Specification

Quantity

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