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STMN2 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR13583G 100 μl / $495

STMN2 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR13583G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STMN2 antibody (N-term).

Molecular Weight

20828 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone Membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Golgi apparatus. Endosome. Cell projection, lamellipodium Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

This STMN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 36-69 amino acids from the N-terminal region of human STMN2.

Isotype

Rabbit Ig

Symbol

SCG10, SCGN10

GeneID

UniProt ID

Function

Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity).

Summary

Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, IHC-P, E

Dilution

IHC-P~~1:25 FC~~1:25 WB~~1:1000

Synonyms

Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10, STMN2, SCG10, SCGN10

Images

Immunohistochemical analysis of paraffin-embedded H. liver section using STMN2 Antibody (N-term)( APR13583G). APR13583G was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.

Flow cytometric analysis of SH-SY5Y cells using STMN2 Antibody (N-term)(green, APR13583G) compared to an isotype control of rabbit IgG(blue). APR13583G was diluted at 1:25 dilution. An Alexa Fluor? 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.

Western blot analysis of lysates from U-87 MG, SH-SY5Y cell line, human brain, mouse brain, rat brain tissue lysate (from left to right), using STMN2 Antibody (N-term)( APR13583G). APR13583G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Specification

Quantity

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