> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > OPA1(form S1) Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR08862G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality OPA1(form S1) antibody (C-term).
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Molecular Weight |
111631 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
This OPA1(form S1) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 895-929 amino acids from the C-terminal region of human OPA1(form S1).
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Isotype |
Rabbit Ig
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Symbol |
KIAA0567
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GeneID |
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UniProt ID |
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Function |
Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space. May also play a role in mitochondrial genome maintenance.
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Summary |
Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Dynamin-like 120 kDa protein, mitochondrial, Optic atrophy protein 1, Dynamin-like 120 kDa protein, form S1, OPA1, KIAA0567
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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