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STRADA Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR07193G 100 μl / $495

STRADA Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR07193G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STRADA antibody (C-term).

Molecular Weight

48369 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm

Host

Rabbit

Species Reactivity

Human, Mouse

Target

This STRADA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 303-346 amino acids from the C-terminal region of human STRADA.

Isotype

Rabbit Ig

Symbol

LYK5 {ECO:0000312|EMBL:AAP42280.1}, STRA

GeneID

UniProt ID

Function

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Summary

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, IF, IHC-P, E

Dilution

IHC-P~~1:25 IF~~1:25 FC~~1:25 WB~~1:1000

Synonyms

STE20-related kinase adapter protein alpha, STRAD alpha, STE20-related adapter protein, Serologically defined breast cancer antigen NY-BR-96, STRADA, LYK5 {ECO:0000312|EMBL:AAP422801}, STRAD

Images

Immunohistochemical analysis of paraffin-embedded H. duodenum section using STRADA Antibody (C-term)( APR07193G). APR07193G was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Fluorescent image of A549 cells stained with STRADA Antibody (C-term)( APR07193G). APR07193G was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor? 555 conjugated with Phalloidin (red).

Flow cytometric analysis of SH-SY5Y cells using STRADA Antibody (C-term)(green, APR07193G) compared to an isotype control of rabbit IgG(blue). APR07193G was diluted at 1:25 dilution. An Alexa Fluor? 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.

Specification

Quantity

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