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CHML Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMM05754G 100 μl / $495

CHML Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMM05754G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CHML antibody (C-term).

Molecular Weight

74071 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytosol

Host

Rabbit

Species Reactivity

Human

Target

This CHML antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 624-656 amino acids from the C-terminal region of human CHML.

Isotype

Rabbit Ig

Symbol

REP2

GeneID

UniProt ID

Function

Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.

Summary

Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, IHC-P, E

Dilution

IHC-P~~1:25 FC~~1:25 WB~~1:1000

Synonyms

Rab proteins geranylgeranyltransferase component A 2, Choroideremia-like protein, Rab escort protein 2, REP-2, CHML, REP2

Images

Immunohistochemical analysis of paraffin-embedded H. stomach section using CHML Antibody (C-term)( AMM05754G). AMM05754G was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Flow cytometric analysis of Hela cells using CHML Antibody (C-term)(green, AMM05754G) compared to an isotype control of rabbit IgG(blue). AMM05754G was diluted at 1:25 dilution. An Alexa Fluor? 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.

Immunohistochemical analysis of paraffin-embedded R. cerebellum section using CHML Antibody (C-term)( AMM05754G). AMM05754G was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Specification

Quantity

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