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Primary Antibody >
Polyclonal Antibodies >
CHML Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM05754G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CHML antibody (C-term).
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Molecular Weight |
74071 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytosol
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
This CHML antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 624-656 amino acids from the C-terminal region of human CHML.
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Isotype |
Rabbit Ig
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Symbol |
REP2
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GeneID |
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UniProt ID |
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Function |
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
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Summary |
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, IHC-P, E
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Dilution |
IHC-P~~1:25
FC~~1:25
WB~~1:1000
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Synonyms |
Rab proteins geranylgeranyltransferase component A 2, Choroideremia-like protein, Rab escort protein 2, REP-2, CHML, REP2
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Images |
Immunohistochemical analysis of paraffin-embedded H. stomach section using CHML Antibody (C-term)( AMM05754G). AMM05754G was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining. Flow cytometric analysis of Hela cells using CHML Antibody (C-term)(green, AMM05754G) compared to an isotype control of rabbit IgG(blue). AMM05754G was diluted at 1:25 dilution. An Alexa Fluor? 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody. Immunohistochemical analysis of paraffin-embedded R. cerebellum section using CHML Antibody (C-term)( AMM05754G). AMM05754G was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining. |
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Specification |
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Quantity |
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