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R Cask Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR13040G 100 μl / $495

R Cask Antibody (Center)

Brand

Leading Biology

Catalog Number

APR13040G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality R Cask antibody (Center).

Molecular Weight

103259 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Rat

Immunogen

589-616 aa

Target

This Rat Cask antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of rat Cask.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.

Summary

Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Peripheral plasma membrane protein CASK, Calcium/calmodulin-dependent serine protein kinase, Cask

Images

Rat Cask Antibody (Center) (Cat. APR13040G) western blot analysis in rat brain tissue lysates (35ug/lane).This demonstrates the Rat Cask antibody detected the Rat Cask protein (arrow).

Specification

Quantity

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