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DRD2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR11787G 100 μl / $495

DRD2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR11787G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DRD2 antibody (C-term).

Molecular Weight

50619 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

307-336 aa

Target

This DRD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the C-terminal region of human DRD2.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

Summary

This gene encodes the D2 subtype of the dopamine receptor.This G-protein coupled receptor inhibits adenylyl cyclase activity.A missense mutation in this gene causes myoclonus dystonia; othermutations have been associated with schizophrenia. Alternativesplicing of this gene results in two transcript variants encodingdifferent isoforms. A third variant has been described, but it hasnot been determined whether this form is normal or due to aberrantsplicing.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

D(2) dopamine receptor, Dopamine D2 receptor, DRD2

Images

All lanes : Anti-DRD2 Antibody (Cterm) at 1:2000 dilution Lane 1: human brain lysate Lane 2: human cerebellum lysate Lane 3: HT-1080 whole cell lysate Lane 4: K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Anti-DRD2 Antibody (C-term) at 1:2000 dilution + K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

All lanes : Anti-DRD2 Antibody (C-term) at 1:2000 dilution Lane 1: human brain lysates Lane 2: K562 whole cell lysates Lane 3: human cerebellum lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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