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GPX3 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR07131G 100 μl / $495

GPX3 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR07131G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GPX3 antibody (Center).

Molecular Weight

25552 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

93-123 aa

Target

This GPX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-123 amino acids from the Central region of human GPX3.

Isotype

Rabbit Ig

Symbol

GPXP

GeneID

UniProt ID

Function

Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.

Summary

This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Glutathione peroxidase 3, GPx-3, GSHPx-3, Extracellular glutathione peroxidase, Plasma glutathione peroxidase, GPx-P, GSHPx-P, GPX3, GPXP

Images

Western blot analysis of lysates from human kidney, plasma, mouse kidney, plasma and rat kidney tissue lysate(from left to right), using GPX3 Antibody (Center)( APR07131G). APR07131G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

GPX3 Antibody (Center) (Cat. APR07131G) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the GPX3 antibody detected the GPX3 protein (arrow).

GPX3 Antibody (Center) (Cat. APR07131G)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GPX3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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