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UNCX Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR13953G 100 μl / $495

UNCX Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR13953G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UNCX antibody (C-term).

Molecular Weight

53690 Da

Cellular Localization

Antigen Cellular Localization: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}

Host

Rabbit

Species Reactivity

Human

Immunogen

382-410 aa

Target

This UNCX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-410 amino acids from the C-terminal region of human UNCX.

Isotype

Rabbit Ig

Symbol

UNCX4.1

GeneID

UniProt ID

Function

Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By similarity).

Summary

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Dilution

IF~~1:25 WB~~1:1000

Synonyms

Homeobox protein unc-4 homolog, Homeobox protein Uncx41, UNCX, UNCX41

Images

Immunofluorescent analysis of U251 cells, using UNCX Antibody (C-term) (Cat. APR13953G). APR13953G was diluted at 1:25 dilution. Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Dylight Fluor? 554 (red) conjugated Phalloidin (red).

UNCX Antibody (C-term) (Cat. APR13953G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the UNCX antibody detected the UNCX protein (arrow).

Specification

Quantity

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