> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CB2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR11263G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CB2 antibody (C-term).
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Molecular Weight |
39681 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Perikaryon Note=Localizes to apical dendrite of pyramidal neurons
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
329-356 aa
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Target |
This CB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-356 amino acids from the C-terminal region of human CB2.
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Isotype |
Rabbit Ig
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Symbol |
CB2A, CB2B
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GeneID |
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UniProt ID |
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Function |
Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
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Summary |
The cannabinoid delta-9-tetrahydrocannabinol is theprincipal psychoactive ingredient of marijuana. The proteinsencoded by this gene and the cannabinoid receptor 1 (brain) (CNR1)gene have the characteristics of a guanine nucleotide-bindingprotein (G-protein)-coupled receptor for cannabinoids. They inhibitadenylate cyclase activity in a dose-dependent, stereoselective,and pertussis toxin-sensitive manner. These proteins have beenfound to be involved in the cannabinoid-induced CNS effects(including alterations in mood and cognition) experienced by usersof marijuana. The cannabinoid receptors are members of family 1 ofthe G-protein-coupled receptors.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
IHC-P~~1:10~50
FC~~1:10~50
WB~~1:1000
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Synonyms |
Cannabinoid receptor 2, CB-2, CB2, hCB2, CX5, CNR2, CB2A, CB2B
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Images |
Immunohistochemical analysis of paraffin-embedded R. brain section using CB2 Antibody(C-term)( APR11263G). APR11263G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
Immunohistochemical analysis of paraffin-embedded H. brain section using CB2 Antibody(C-term)( APR11263G). APR11263G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
Flow cytometric analysis of Jurkat cells using CB2 Antibody (C-term) (Cat. APR11263G) compared to an isotype control of rabbit IgG(blue). APR11263G was diluted at 1:25 dilution. An Alexa Fluor? 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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