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PHTNS Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMM07168G 100 μl / $495

PHTNS Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMM07168G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PHTNS antibody (N-term).

Molecular Weight

67943 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cytoplasm, cytoskeleton

Host

Rabbit

Species Reactivity

Human

Immunogen

192-220 aa

Target

This PHTNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-220 amino acids from the N-terminal region of human PHTNS.

Isotype

Rabbit Ig

Symbol

HKMT1098, KIAA1949

GeneID

UniProt ID

Function

Isoform 1: May target protein phosphatase 1 to F-actin cytoskeleton.

Summary

PHTNS interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin cytoskeleton。

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Phostensin, Protein phosphatase 1 F-actin cytoskeleton-targeting subunit, Protein phosphatase 1 regulatory subunit 18, PPP1R18, HKMT1098, KIAA1949

Images

Western blot analysis of PHTNS Antibody (N-term) (Cat. AMM07168G) in Ramos cell line lysates (35ug/lane). PHTNS (arrow) was detected using the purified Pab.

PHTNS Antibody (N-term) (Cat. AMM07168G) IHC analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PHTNS Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

PHTNS Antibody (N-term) (Cat. AMM07168G) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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