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TMIE Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR13758G 100 μl / $495

TMIE Antibody (Center)

Brand

Leading Biology

Catalog Number

APR13758G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TMIE antibody (Center).

Molecular Weight

17241 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

71-100 aa

Target

This TMIE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the Central region of human TMIE.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Unknown. The protein may play some role in a cellular membrane location. May reside within an internal membrane compartment and function in pathways such as those involved in protein and/or vesicle trafficking. Alternatively, the mature protein may be localized in the plasma membrane and serve as a site of interaction for other molecules through its highly charged C-terminal domain.

Summary

This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Transmembrane inner ear expressed protein, TMIE

Images

Anti-TMIE Antibody (Center) at 1:1000 dilution + human kidney lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 17 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of TMIE Antibody (Center) (Cat. APR13758G) in mouse liver tissue lysates (35ug/lane). TMIE (arrow) was detected using the purified Pab.

Specification

Quantity

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