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TBCE Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR13712G 100 μl / $495

TBCE Antibody (Center)

Brand

Leading Biology

Catalog Number

APR13712G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TBCE antibody (Center).

Molecular Weight

59346 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cytoplasm, cytoskeleton

Host

Rabbit

Species Reactivity

Human

Immunogen

364-392 aa

Target

This TBCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-392 amino acids from the Central region of human TBCE.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicated in the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation.

Summary

Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Tubulin-specific chaperone E, Tubulin-folding cofactor E, TBCE

Images

TBCE Antibody (Center) (Cat. APR13712G) western blot analysis in CEM,K562 cell line lysates (35ug/lane).This demonstrates the TBCE antibody detected the TBCE protein (arrow).

Specification

Quantity

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