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KCNH2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM06113G 100 μl / $495

KCNH2 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM06113G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNH2 antibody (Center).

Molecular Weight

126655 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

861-888 aa

Target

This KCNH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 861-888 amino acids from the Central region of human KCNH2.

Isotype

Rabbit Ig

Symbol

ERG, ERG1, HERG

GeneID

UniProt ID

Function

Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.

Summary

KCNH2 is a voltage-activated potassium channel belonging to the eag family.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Synonyms

Potassium voltage-gated channel subfamily H member 2, Eag homolog, Ether-a-go-go-related gene potassium channel 1, ERG-1, Eag-related protein 1, Ether-a-go-go-related protein 1, H-ERG, hERG-1, hERG1, Voltage-gated potassium channel subunit Kv111, KCNH2, ERG, ERG1, HERG

Images

Western blot analysis of KCNH2 Antibody (Center) (Cat. AMM06113G) in CEM cell line lysates (35ug/lane).KCNH2 (arrow) was detected using the purified Pab.

KCNH2 Antibody (Center) (Cat. AMM06113G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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