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ITPKA Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR16947G 100 μl / $495

ITPKA Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR16947G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITPKA antibody (C-term).

Molecular Weight

51009 Da

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

345-375 aa

Target

This ITPKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of human ITPKA.

Isotype

Rabbit Ig

GeneID

UniProt ID

Summary

ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Inositol-trisphosphate 3-kinase A, Inositol 1, 5-trisphosphate 3-kinase A, IP3 3-kinase A, IP3K A, InsP 3-kinase A, ITPKA

Images

All lanes : Anti-ITPKA Antibody (C-term) at 1:1000 dilution Lane 1: human brain lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of hITPKA-E360 (Cat. APR16947G) in K562 cell line and mouse lung tissue lysates (35ug/lane). ITPKA (arrow) was detected using the purified Pab.

Specification

Quantity

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