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PI3KR5 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM07182G 100 μl / $495

PI3KR5 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM07182G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PI3KR5 antibody (Center).

Molecular Weight

97348 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

392-421 aa

Target

This PI3KR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 392-421 amino acids from the Central region of human PI3KR5.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG (By similarity).

Summary

PI3KR5 is a regulatory subunit of the PI3K gamma complex. This protein, which interacts with G beta gamma proteins, is a heterodimer of a catalytic subunit (PI3KCG/p120) and a regulatory (PI3KR5a/p101) subunit.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Phosphoinositide 3-kinase regulatory subunit 5, PI3-kinase regulatory subunit 5, PI3-kinase p101 subunit, Phosphatidylinositol 4, 5-bisphosphate 3-kinase regulatory subunit, PtdIns-3-kinase regulatory subunit, Protein FOAP-2, PtdIns-3-kinase p101, p101-PI3K, PIK3R5

Images

Western blot analysis of PI3KR5 Antibody (Center) Pab (Cat. AMM07182G) in K562 cell line lysates (35ug/lane). PI3KR5(arrow) was detected using the purified polyclonal antibody.

Western blot analysis of PIK3R5 (arrow) using rabbit polyclonal PIK3R5 Antibody (Center) (Cat. AMM07182G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PIK3R5 gene (Lane 2).

Specification

Quantity

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