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RBM3 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMR09699G 100 μl / $495

RBM3 Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMR09699G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RBM3 antibody (C-term).

Molecular Weight

17170 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Cell projection, dendrite Note=Localizes in mRNA granules in dentrites.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

128-157 aa

Target

This RBM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the C-terminal region of human RBM3.

Isotype

Rabbit Ig

Symbol

RNPL

GeneID

UniProt ID

Function

Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation (By similarity).

Summary

RBM3 is a member of the glycine-rich RNA-binding protein family and a protein with one RNA recognition motif (RRM) domain. Expression of this protein is induced by cold shock and low oxygen tension.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Putative RNA-binding protein 3, RNA-binding motif protein 3, RNPL, RBM3, RNPL

Images

Western blot analysis of RBM3 Antibody (C-term) (Cat. 3AMR09699G) in Hela cell line lysates and mouse NIH-3T3 tissues lysates(35ug/lane). RBM3 (arrow) was detected using the purified Pab.

RBM3 Antibody (C-term) (RB18777) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RBM3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

RBM3 Antibody (C-term) (Cat. AMR09699G) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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