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DCAMKL1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR11254G 100 μl / $495

DCAMKL1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR11254G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DCAMKL1 antibody (N-term).

Molecular Weight

82224 Da

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

1-30 aa

Target

This DCAMKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DCAMKL1.

Isotype

Rabbit Ig

Symbol

DCAMKL1, DCDC3A, KIAA0369

GeneID

UniProt ID

Function

Probable kinase that may be involved in a calcium- signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.

Summary

Doublecortin-like kinase (DCAMKL1)(Ser/Thr protein kinase family) is essential for proper neurogenesis, neuronal migration, and axonal wiring. DCAMKL1 is involved in a calcium-signaling pathway controling neuronal migration in the developing brain, and participates in functions of the mature nervous system. DCAMKL1 protein shares high homology with doublecortin (DCX). DCLK, but not DCX, is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. DCAMKL1 controls mitotic division by regulating spindle formation and also determines the fate of neural progenitors during cortical neurogenesis.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Serine/threonine-protein kinase DCLK1, Doublecortin domain-containing protein 3A, Doublecortin-like and CAM kinase-like 1, Doublecortin-like kinase 1, DCLK1, DCAMKL1, DCDC3A, KIAA0369

Images

Western blot analysis of DCAMKL1 Antibody (N-term)(Cat. APR11254G) in mouse brain tissue lysate. DCAMKL1 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

DCAMKL1 Antibody (D13) (Cat. APR11254G) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the DCAMKL1 antibody detected the DCAMKL1 protein (arrow).

Specification

Quantity

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