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AK7 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR14891G 100 μl / $495

AK7 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR14891G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AK7 antibody (C-term).

Molecular Weight

82658 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytosol

Host

Rabbit

Species Reactivity

Human

Immunogen

629-656 aa

Target

This AK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-656 amino acids from the C-terminal region of human AK7.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.

Summary

The adenylate kinases (AK) are a family of structurally and functionally related enzymes that catalyze a similar reaction, MgNTP + AMP = MgNDP + ADP (N = A or G). The AK enzymes are important for maintenance of homeostasis of the adenine and guanine nucleotide pools. AK1 is a cytosolic enzyme for which ATP is the substrate. AK2 catalyzes the same reaction as AK1, but it is localized in the mitochondrial intermembrane space. AK3 is present in the mitochondrial matrix and prefers GTP over ATP as the substrate.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Adenylate kinase 7, AK 7, ATP-AMP transphosphorylase 7, AK7

Images

Western blot analysis of anti-AK7 Antibody (C-term) (Cat. APR14891G) in K562 cell line lysates (35ug/lane).AK7(arrow) was detected using the purified Pab.

AK7 Antibody (C-term) (Cat. APR14891G) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AK7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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