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IFNGR2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR07951G 100 μl / $495

IFNGR2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR07951G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IFNGR2 antibody (C-term).

Molecular Weight

37806 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

308-337 aa

Target

This IFNGR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human IFNGR2.

Isotype

Rabbit Ig

Symbol

IFNGT1

GeneID

UniProt ID

Function

Part of the receptor for interferon gamma. Required for signal transduction. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2.

Summary

IFNGR2 is the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Interferon gamma receptor 2, IFN-gamma receptor 2, IFN-gamma-R2, Interferon gamma receptor accessory factor 1, AF-1, Interferon gamma transducer 1, IFNGR2, IFNGT1

Images

Western blot analysis of lysate from human skeletal muscle tissue lysate, using IFNGR2 Antibody (C-term)( APR07951G). APR07951G was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.

Western blot analysis of lysate from human skeletal muscle tissue lysate, using IFNGR2 Antibody (C-term)( APR07951G). APR07951G was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.

Western blot analysis of IFNGR2 Antibody (C-term) (Cat. APR07951G) in MDA-MB453 cell line lysates (35ug/lane). IFNGR2 (arrow) was detected using the purified Pab.

Specification

Quantity

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