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CRAT Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APG02760G 100 μl / $495

CRAT Antibody (N-term)

Brand

Leading Biology

Catalog Number

APG02760G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRAT antibody (N-term).

Molecular Weight

70858 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum. Peroxisome. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side Isoform 2: Peroxisome.

Host

Rabbit

Species Reactivity

Human

Immunogen

66-96 aa

Target

This CRAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human CRAT.

Isotype

Rabbit Ig

Symbol

CAT1

GeneID

UniProt ID

Function

Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.

Summary

CRAT is carnitine acetyltransferase (CRAT), which is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Carnitine O-acetyltransferase, Carnitine acetylase, Carnitine acetyltransferase, CAT, CrAT, CRAT, CAT1

Images

Western blot analysis of CRAT antibody (N-term) (Cat. APG02760G) in CEM cell line lysates (35ug/lane). CRAT (arrow) was detected using the purified Pab.

CRAT Antibody (N-term) (Cat. APG02760G) IHC analysis in formalin fixed and paraffin embedded human Skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRAT Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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