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UDB17 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM08416G 100 μl / $495

UDB17 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM08416G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UDB17 antibody (Center).

Molecular Weight

61095 Da

Cellular Localization

Antigen Cellular Localization: Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

119-147 aa

Target

This UDB17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-147 amino acids from the Central region of human UDB17.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The major substrates of this isozyme are eugenol > 4-methylumbelliferone > dihydrotestosterone (DHT) > androstane-3-alpha,17-beta-diol (3-alpha-diol) > testosterone > androsterone (ADT).

Summary

UGT2B17 belongs to the family of UDP-glucuronosyltransferases (UGTs; EC 2.4.1.17), enzymes that catalyze the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a variety of substrates, including steroid hormones.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

UDP-glucuronosyltransferase 2B17, UDPGT 2B17, C19-steroid-specific UDP-glucuronosyltransferase, C19-steroid-specific UDPGT, UGT2B17

Images

Western blot analysis of UDB17 antibody (Center) (Cat. AMM08416G) in Y79 cell line lysates (35ug/lane). UDB17 (arrow) was detected using the purified Pab.

UDB17 Antibody (Center) (Cat. AMM08416G) IHC analysis in formalin fixed and paraffin embedded human Prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UDB17 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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